PhenoAge Biological Age Calculator
Enter the 9 blood biomarkers from your most recent lab panel (US units) plus your chronological age. The formula is the peer-reviewed PhenoAge method from Levine et al., Aging (Albany NY), 2018.
Fill in all 10 fields above to compute your PhenoAge biological age. All values come from a standard comprehensive blood panel (CBC + CMP + lipids + hs-CRP).
Educational tool, not a medical diagnosis. PhenoAge is validated against all-cause mortality in NHANES + UK Biobank cohorts. Most actionable markers to lower it: hs-CRP, fasting glucose, albumin (protein status), lymphocyte% (immune health). Improvement of 0.5–2 years over 6 months is realistic with consistent lifestyle change.
What does the result mean?
PhenoAge is an estimate of how your body has aged biologically, derived from 9 inflammation, metabolic, kidney, liver, and hematology markers. If your PhenoAge is lower than your chronological age, you are aging more slowly than average for your cohort. If higher, the model is flagging measurable wear: chronic inflammation, glycation, kidney stress, or red-cell volume drift. None of this is destiny — every biomarker is modifiable.
Frequently asked questions
- What is PhenoAge?
- PhenoAge is a biological-age estimate published by Morgan Levine and colleagues in 2018 (Aging, Albany NY). It combines 9 standard blood biomarkers plus chronological age into a single number — your estimated phenotypic age — using a peer-reviewed Cox-regression mortality model. A PhenoAge below your chronological age suggests slower-than-average biological aging.
- What blood markers do I need?
- Ten inputs total: chronological age, albumin (g/dL), creatinine (mg/dL), fasting glucose (mg/dL), high-sensitivity CRP (mg/L), lymphocyte percentage (%), mean cell volume / MCV (fL), red-cell distribution width / RDW (%), alkaline phosphatase / ALP (U/L), and white blood cell count (1000 cells/µL). Every input comes from a standard CBC and basic metabolic panel — most are on a routine annual blood test.
- How accurate is PhenoAge?
- The PhenoAge model was trained on NHANES III and validated on NHANES IV. In the original paper, it predicted 10-year all-cause mortality with a hazard ratio of ~1.09 per year of accelerated PhenoAge, after adjusting for chronological age and other risk factors. It outperformed earlier blood-based biological age clocks. It's a population-level estimator — a single result is informative, but trend over time is more actionable.
- Is this the same calculator embedded in your blog post?
- Yes. The same React component powers the calculator on /blog/biological-age-calculator-blood-test (where it sits in a fuller editorial article). This /tools page is the standalone version — same formula, same accuracy, no surrounding article. Use whichever context you prefer.
- Does Merios store my numbers?
- No. The calculator runs entirely in your browser. Your inputs never leave your device and are not sent to a server. Reload the page and the values are cleared.
Reference: Levine ME, Lu AT, Quach A, et al. An epigenetic biomarker of aging for lifespan and healthspan. Aging (Albany NY). 2018;10(4):573-591. doi:10.18632/aging.101414
Track this in Merios
One PhenoAge today is information. Twelve PhenoAges over a year is a trend.
Merios reads your blood tests automatically, recalculates PhenoAge with each upload, and tracks the curve — so you can see if a protocol is actually moving the needle.
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